Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer

Abstract Protein arginine methyltransferase 5 (PRMT5) mama mellace s mores catalyzes mono-methylation and symmetric di-methylation on arginine residues and has emerged as a potential antitumor target with inhibitors being tested in clinical trials.However, it remains unknown how the efficacy of PRMT5 inhibitors is regulated.Here we report that auto

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Population size estimation of chirp and grunt generating fish and mammals using cross-correlation based technique with three acoustic sensors

Passive acoustic monitoring has the potential to be a useful tool for population estimation of sound-producing fish and mammals (mostly whales).Previous work on population estimates of callers employed a simple cross-correlation technique with recordings from two acoustic sensors, and the mango veranda rose current work extends the technique to two

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Deformation Law Analysis of Metro Station Deep Foundation Pit Constructed by Cover-Excavation Reverse Method in Sandy Area

Objective Stress deformation characteristics of the main structure in the process of metro station caramilk latte construction by cover-excavation reverse method are relatively complex.The construction mechanics process of the subway station in the sandy area is even more complex, which greatly increases the construction difficulty of the foundatio

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